Superparamagnetic Iron Oxide Nanoparticles with Rigid Cross-linked Polyethylene Glycol Fumarate Coating for Application in Imaging and Drug Delivery
نویسندگان
چکیده
Morteza Mahmoudi,*,† Abdolreza Simchi,*,†,‡ Mohammad Imani,§ and Urs O. Häfeli Institute for Nanoscience and Nanotechnology, Sharif UniVersity of Technology, Tehran, Iran, Department of Materials Science and Engineering, Sharif UniVersity of Technology, Tehran, Iran, NoVel Drug DeliVery Systems Department, Iran Polymer and Petrochemical Institute, Tehran, Iran, Faculty of Pharmaceutical Sciences, UniVersity of British Columbia, VancouVer, British Columbia, Canada
منابع مشابه
ANALYTICAL STUDY OF EFFECT OF BILAYER INORGANIC AND ORGANIC COATING AROUND THE IRON OXIDE NANOPARTICLES ON MAGNETIC RESONANCE IMAGING CONTRAST
Background & Aims: In recent years, iron oxide nanoparticles have been used in contrast-enhanced magnetic resonance imaging for diagnosing a wide range of diseases. In order to provide biocompatibility and prevent the toxicity of the nanoparticles, using organic or inorganic coating around these nanoparticles is important for their application. The aim of this study is to investigate the effect...
متن کاملEffect of coating thickness of iron oxide nanoparticles on their relaxivity in the MRI
Objective(s):Iron oxide nanoparticles have found prevalent applications in various fields including drug delivery, cell separation and as contrast agents. Super paramagnetic iron oxide (SPIO) nanoparticles allow researchers and clinicians to enhance the tissue contrast of an area of interest by increasing the relaxation rate of water. In this study, we evaluate the dependency of hydrodynamic si...
متن کاملMagnetic iron oxide nanoparticles, Polyethylene glycol, Surfactant, Superparamagnetic, Chemical co-precipitation
In this study, magnetic iron oxide nanoparticles (Fe3O4) with the size range of 20-30 nm were prepared by the modified controlled chemical co-precipitation method from the solution of ferrous/ferric mixed salt-solution in alkaline medium. In this process polyethylene glycol was used as a surfactant to prevent the solution from agglomeration. The prepared magnetic nanoparticles were characterize...
متن کاملPreparation and characterization of PEG/Dextran coated superparamagnetic Iron Oxide (Fe3O4) nanoparticles for biomedical applications
Recent progress in nanotechnology and electrochemical methods can be applied to fine control of the size, crystal structure, and surface properties of iron oxide nanoparticles. Here we appliedcathodic electrochemical deposition (CED) as an efficient and effective tactic for synthesisand double coating of surface of superparamagnetic iron oxide nanoparticles (SPIONs). In first step, bare Fe3O4 n...
متن کاملPreparation and characterization of PEG/Dextran coated superparamagnetic Iron Oxide (Fe3O4) nanoparticles for biomedical applications
Recent progress in nanotechnology and electrochemical methods can be applied to fine control of the size, crystal structure, and surface properties of iron oxide nanoparticles. Here we appliedcathodic electrochemical deposition (CED) as an efficient and effective tactic for synthesisand double coating of surface of superparamagnetic iron oxide nanoparticles (SPIONs). In first step, bare Fe3O4 n...
متن کامل